高分子科学前沿讲座2022年第二期将于2022年5月5日上午8:30-9:15在线上召开，由肖海华老师邀请美国耶鲁大学周江兵副教授作报告。

高分子科学前沿讲座2022年第三期将于2022年5月5日上午9:15-10:00在线上召开，由肖海华老师邀请美国威斯康星大学蔡伟波教授作报告。

会议号均为307-618-765.

周江兵, 美国耶鲁大学脑外系及生物医学工程副教授（有终身教职）, 主要从事致力于研究开发基因递送，脑部靶向给药，口服给药相关纳米技术及应用这些技术治疗神经系统疾病 （网站：https://medicine.yale.edu/lab/zhou/）。目前已发表学术论文近70篇，，包括多篇发表在高水平杂志，如Nature, Nature Materials, Nature Cell Biology, Nature Biomedical Engineering, Nature Communications, PNAS, and Advanced Materials。此外，实验室的多项专利技术成功实现对工业界转让。

报告摘要：Drug delivery to the brain is a major challenge, because the brain possesses the blood-brain barrier (BBB), which prevents the penetration of most drugs into the brain. In this talk, I will introduce a serial of techniques established in my laboratory for drug delivery to the brain through locoregional, intravenous, or oral administration. I will give a few examples to show how these techniques can be utilized for delivery of therapeutic agents to the brain for treatment of brain cancer or stroke.

蔡伟波, 美国威斯康星大学麦迪逊分校（University of Wisconsin-Madison）放射学系、医学物理学系、材料科学与工程系、药学系的Vilas杰出成就教授（有终身教职）, 主要从事分子影像, 诊疗一体化，及生物纳米科技的研究（网站：http://mi.wisc.edu）。目前已发表学术论文360余篇, 论文被引用30000余次，H-index 为95。部分奖项包括 FAIMBE， FSNMMI， FRSC 等。蔡伟波教授所指导的本科生，博士生，博士后和访问学者已经累计获得超过130项学术奖励, 其中十多位已经在世界知名院校 独立建组开展研究工作。

报告摘要：The Molecular Imaging and Nanotechnology Laboratory at the University of Wisconsin - Madison (http://mi.wisc.edu/) is mainly focused on three areas: 1) development of multimodality molecular imaging agents; 2) nanobiotechnology and its biomedical applications; and 3) molecular therapy of cancer and various other diseases. In this talk, I will present our recent work on molecular imaging and image-guided drug delivery of cancer and other diseases with peptides, proteins, and a variety of nanomaterials. The primary imaging techniques used in these studies are positron emission tomography (PET), photoacoustic tomography (PAT), optical imaging, and magnetic resonance imaging (MRI). Some molecular targets that we have investigated are CD105 (i.e. endoglin), PD-1/PD-L1, CTLA-4, CD146, VEGFR, integrin αvβ3, among others. The nanomaterials that will be discussed in this presentation may include silica-based nanoparticles, DNA nanomaterials, nanovaccines, micelles, iron oxide nanoparticles, 2-D nanomaterials, hybrid nanomaterials, among others.