A Robust Strategy for Precise Fabrication of Rigid–Flexible Coupling Dendrimers toward Self-Coordinated Hierarchical Assembly

文章来源: 发布时间:2021-01-22

Xing Wang, Peiyuan Gao, Juan Wang, Yanyu Yang*, Yezi You*, Decheng Wu*

CCS Chemistry 2020, 2, 1093–1104

Advances in nanotechnology depend upon expanding the ability to create biologically inspired complex materials with well-defined multidimensional structures. Fabrication of hybrid hierarchical structures by combining colloidal organic and inorganic building blocks remains a challenge due to the difficulty in preparing a diverse spectrum of rigid–flexible coupling units of precise shape and size. Here we report a general strategy for crafting a myriad of uniform aggregates via manipulating self-assembly of distinct dendrimers with precisely controlled polyhedral oligomeric silsesquioxane (POSS)-embedded cores integrating stiffness and ductility. The rigidity of POSS units exerts steric effects on self-amplification of hydrophobic domains while the flexibility from internally ductile linkages provides ideal scenarios in establishing self-adaptive structural optimization, which subsequently drive the assemblies to proceed into hierarchical self-assembly via multiple coordination effects, generating highly complex multicompartment micelles without any preprocessing. Our facile approach enables a robust modular nanofabrication of well-organized dendrimers toward artificial functional systems with defined geometric architectures and intriguing functions for advanced biological applications.

文章链接:https://www.chinesechemsoc.org/doi/full/10.31635/ccschem.020.202000238